Peroxisome Proliferator–Activated Receptors and The Metabolic Syndrome
نویسندگان
چکیده
منابع مشابه
Cannabinoid activation of peroxisome proliferatoractivated receptors: an update and review of the physiological relevance
Since 2002, evidence has been building that cannabinoids, including endocannabinoids and endocannabinoid-like compounds, phytocannabinoids and synthetic cannabinoid ligands, bind to and activate the different isoforms of the nuclear receptors, peroxisome proliferator-activated receptors (PPARs; α, β, and γ ). This has been shown through the use of reporter gene assays, binding studies, the use ...
متن کاملMetabolic syndrome and type 2 diabetes mellitus: focus on peroxisome proliferator activated receptors (PPAR)
The metabolic syndrome is a highly prevalent clinical entity. The recent Adult Treatment Panel (ATP III) guidelines have called specific attention to the importance of targeting the cardiovascular risk factors of the metabolic syndrome as a method of risk reduction therapy. The main factors characteristic of this syndrome are abdominal obesity, atherogenic dyslipidemia, elevated blood pressure,...
متن کاملMinireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors.
Lipid and carbohydrate homeostasis in higher organisms is under the control of an integrated system that has the capacity to rapidly respond to metabolic changes. The peroxisome proliferator-activated receptors (PPARs) are nuclear fatty acid receptors that have been implicated to play an important role in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronar...
متن کاملPeroxisome Proliferator-Activated Receptors (PPARs): Choreographers of Metabolic Gene Transcription
Nuclear receptors are ligand-activated transcription factors that regulate gene expression in response to small lipophilic compounds such as testosterone [androgen receptor (AR)], oxysterols [liver X receptor (LXR)], estrogen (ER), xenobiotics [pregnane X receptor (PXR)], retinoic acid (RAR), thyroid hormone (TR), bile acids [farnesoid X receptor (FXR)] and vitamin D (VDR). The peroxisome proli...
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ژورنال
عنوان ژورنال: The Indonesian Biomedical Journal
سال: 2009
ISSN: 2355-9179,2085-3297
DOI: 10.18585/inabj.v1i1.79